First off, before you even start, make sure you don't shock your motherboard with static electricity. Static can easily fry your parts, so touching something metal to ground yourself or using a special wristband can save you a lot of trouble.
Next, when you're putting the motherboard in your computer case, you've got to be careful to line everything up perfectly and screw it in without forcing it. This keeps it stable and stops it from getting damaged.
It's also super important to get your CPU (the brain of your computer) and your RAM (short-term memory) installed just right. If these aren't put in correctly or if they're the wrong kind for your motherboard, your computer won't work as it should. Always check the manual to make sure you're doing it right.
Cables can be a pain, but you've got to make sure they're all hooked up right and not in the way of anything. Messy cables can block air getting to your parts, making them hotter than they should be, which isn't good. Plus, you don't want them causing a short circuit.
Don't forget about standoffs – these little spacers keep your motherboard from touching the case directly, which could cause a short circuit. Make sure they're all in the right spots before you screw your motherboard in.
Lastly, putting thermal paste on your CPU is really important for keeping it cool. You don't need a lot, just enough to cover the top. Putting on too much or too little can make your CPU overheat, and nobody wants that.
In short, if you're careful with static electricity, make sure everything's lined up and not forced, get your CPU and RAM in right, manage your cables well, use standoffs, and apply the right amount of thermal paste, you'll be setting up your motherboard the right way. Follow these steps, and you'll be on your way to building a great computer.
https://www.pcworld.com/article/2266284/avoid-these-6-mistakes-when-installing-the-mainboard.html